Numerous studies link carotenoids - yellow, orange, red, and green pigments in fruits and vegetables - to reduced risks of aggressive and threatening conditions, an enhanced defence system, and tissue protection. Fruits and vegetables are the best sources of carotenoids, but most people do not eat the 5-9 daily servings recommended for optimal well-being. GNLD’s Carotenoid Complex is a whole-food supplement whose benefits have been demonstrated in human studies conducted by USDA and university researchers. Each capsule provides the complete carotenoid value of an optimal serving of a wide variety of carotenoid-rich fruits and vegetables.
United States Department of Agriculture (USDA) scientists conducted clinical research studies on Carotenoid Complex, GNLD’s exclusive broad-spectrum carotenoid supplement from whole foods, and published their findings in peer-reviewed scientific journals. The USDA studies showed that Carotenoid Complex:
Sometimes called “nature’s crayons,” carotenoids are a huge family of colourful plant pigments, many of which act as precursors of vitamin A. Carotenoids are responsible for the red in tomatoes, the orange in carrots, and the yellow in squash. They are also present in green plants such as spinach, where they are obscured, or masked, by green chlorophyll. About 600 carotenoids have been identified so far - 50-60 of which appear in our food supply.
Some carotenoid-rich fruits and vegetables include:
Apricots, Red bell peppers, Lettuce (red or green leaf romaine), Arugula, Oranges, Spinach, Broccoli, Mangoes, Strawberries, Brussels sprouts, Mustard greens, Sweet potatoes, Butternut squash, Nectarines, Swiss chard, Cantaloupe, Papayas, Tangerines, Carrots, Tomatoes, Parsley, Collard greens, Dandelion greens, Turnip greens, Guavas, Peaches, Pink grapefruit, Yellow bell peppers, Kale, Yellow corn, Watercress, Pumpkin.
The first clues linking carotenoids and health appeared in the 1970s. Researchers observing populations around the world found that in areas where diets were high in fruits and vegetables, the rates for certain aggressive threats to overall well being were low. Conversely, in populations where fruit and vegetable intake was low, the rates of these conditions were high. These findings spurred many new research efforts focusing on different aspects of the diet/disease equation, including high-fibre versus low-fat consumption, vegetarian versus meat diets, and the intake of specific nutrients found in fruits and vegetables - especially beta-carotene.
Beta-carotene quickly became a “star” in both scientific literature and the media, as research showed that diets high in beta-carotene-rich foods clearly offered health benefits distinct from those provided by other dietary factors. But while beta-carotene is the most famous carotenoid, it is just one member of a large “family” with about 600 members, including alpha-, gamma-, and zeta-carotene, lycopene, lutein, zeaxanthin, and beta-cryptoxanthin. Research continues to unravel healthful roles for the other carotenoid family members, as well as beta-carotene.
Beta-carotene never appears in isolation in fruits and vegetables, and neither do the other carotenoids. Broad-spectrum carotenoids work together in fruits and vegetables to promote health, with optimal levels and ratios of each required for optimal protection.
Carotenoids are especially important to the health, growth, and longevity of cells. They may protect us in many distinct ways:
Recognizing the impressive benefits of a diet high in carotenoid-rich fruits and vegetables, health experts have established a series of official dietary recommendations.
Clear as these recommendations are, it remains equally clear that they aren’t being met.
In fact, although some experts recommend consuming at least 6 mg of carotenoids daily, scientists estimate that most of us are actually getting only about 1.5 mg per day - a significant carotenoid gap.
Research shows that fruits and vegetables confer most of the protection in our diets. It also reveals that fruits and vegetables are the food items most often missing from our diets. To help bridge that gap and take advantage of the fact that human-food-chain fruits and vegetables have a built-in long history of safe use, GNLD set out to identify those fruits and vegetables traditionally eaten by humans that would deliver significant amounts of the different members of the carotenoid family. The result is Carotenoid Complex, the first and only product to deliver the full spectrum of carotenoids in a whole food supplement! Each capsule provides the complete carotenoid value of an optimal serving of a wide variety of carotenoid-rich fruits and vegetables.
Following nature’s “blueprint”, GNLD scientists designed Carotenoid Complex using whole foods, not isolated carotenoids such as beta-carotene. Single carotenoids do not occur in isolation in natural foods; they occur with their other carotenoid “family members.” In fact, the importance and uniqueness of the carotenoid group lies in their family structure - each member contributes protective effects and works together as a team to provide maximum benefits.
Painstaking research of whole foods found in the human food chain that are naturally rich in carotenoids led to the development of an optimal carotenoid profile based on an ideal serving of fruits and vegetables. Carotenoid Complex does not contain synthetics or derivatives from plant sources humans do not normally eat. Before formulating Carotenoid Complex, our Scientific Advisory Board and Global Science Network members analyzed naturally occurring fruit and vegetable extracts and concentrates from all over the world to determine those foods that provided the highest levels of carotenoids. These include:
Carotenoid Complex is formulated so each capsule matches the carotenoid profile of an optimal serving of the carotenoid-rich foods listed above. Raw materials were carefully selected to contribute 15 powerful representatives of all the members of the carotenoid family:
The above members fall into the following categories:
Many factors affect absorption of carotenoids in the diet. For example, in raw fruits and vegetables, carotenoids are bound to proteins - as little as 1% of the beta-carotene in raw carrots may be absorbed. On average, your body only absorbs 5-10% of the carotenoids from raw fruits and vegetables.
What’s more, very high levels of a single carotenoid can inhibit absorption of other important carotenoids. High intakes of beta-carotene alone can negatively effect the body’s utilization of other carotenoids.
Research has shown that carotenoids which are concentrated and delivered in a lipid (oil) form are more efficiently absorbed than those that have been concentrated and delivered in either solid/sliced raw form or juice form. Carotenoid Complex uses oil-soluble fruit and vegetable extracts and concentrates in a base of pure olive oil to maximize carotenoid absorption. In a bioavailability study conducted at the University of Nevada, Reno, Carotenoid Complex was shown to be completely bioavailable by the human body. GNLD's SAB member Arianna Carughi took part in the study and reported the results at the annual FASEB meeting.8
GNLD’s own clinical research, plus other studies done by researchers from the USDA, have demonstrated beyond a doubt that Carotenoid Complex is absorbed by the body better than the carotenoids naturally found in raw whole foods.(1, 2)
When it comes to delivering pure carotenoid power, Carotenoid Complex puts loads of kilograms in the palm of your hand. To deliver the total carotenoid power in a single bottle of the new Carotenoid Complex, you’d have to eat:
115 kilograms or more of the raw vegetables and fruits it’s made from. Research shows that your body absorbs only 5-10% of the carotenoids in raw vegetables and fruits.
22 kilograms or more of the steamed vegetables and fruits Carotenoid Complex is made from. Research shows food preparation affects carotenoid bioavailability. Steamed fruits and vegetables increase bioavailability up to 30-50%.
8 kilograms or more of steamed and puréed fruits and vegetables (baby food). Steamed and puréed fruits and vegetables have the best bioavailability - up to 70%, which is the method of raw material preparation utilized in Carotenoid Complex.
At every stage of production - from raw materials and ingredients processing through encapsulation and packaging - GNLD’s Carotenoid Complex is a study in state-of-the-art technology and quality control. The result? What we call our NutriMax Process delivers the most of the best, in each and every capsule!
Due to the strength of independent research studies and the leading-edge technology that the product represents, GNLD was able in 1996 to demonstrate to patent examiners in the United Kingdom that Carotenoid Complex is a unique, advanced nutritional supplement. The result was the issuance of British patent no. 2,274,235, protecting Carotenoid Complex from imitation.
“This invention is a composition useful as a dietary supplement which provides adequate carotenoid ingestion to persons regardless of the inadequacy of their diets with respect to their vegetable intake,” says the patent. “The composition of this invention not only provides adequate quantities of known carotenoids to the diet, but it additionally provides the natural level of lesser known and even unknown carotenoids so that the ingestion of a full spectrum of carotenoids in naturally balanced proportions is achieved by supplementing the diet with the composition of this invention.”
This patent further validates the importance of the invention of Carotenoid Complex and underscores the uniqueness of the technology it reflects. It is truly the one and only product of its type in the world, and you can be proud that it is a GNLD exclusive!
Carotenoid Complex is the most thoroughly tested carotenoid supplement on the market. It has been tested in clinical studies by government and university scientists and shown to have amazing health-protecting powers. Scientists at the United States Department of Agriculture and several universities have shown that Carotenoid Complex may assist in boosting the immune system, protecting the heart, and defending the cells:
Studies conducted by the United States Department of Agriculture (USDA) scientists showed that a carotenoid-deficient diet compromises immune power and that the broad spectrum of carotenoids in Carotenoid Complex could enhance the immune response of otherwise healthy people. The results were presented at the Federation of American Societies of Experimental Biology (FASEB) meeting in April of 1995 in Atlanta, Georgia and later published in the American Journal of Clinical Nutrition. The studies showed that Carotenoid Complex dramatically enhanced both immune cell levels and overall immune cell responsiveness.
First, supplementation with Carotenoid Complex boosted levels of a particular type of white blood cell, lymphocytes, which are the body’s first immunologic line of defense against disease. Supplementation with Carotenoid Complex resulted in natural killer cell levels that were more than 21% above baseline values in just 20 days - more than twice the effect of beta-carotene alone!
Second, Carotenoid Complex reclaimed immune power lost to carotenoid deficiency, and boosted carotenoid levels above baseline (“normal”) levels when compared to diet alone. Supplementation with beta-carotene alone did not provide this benefit.(6,7)
This study, conducted by researchers from the USDA and the University of California, Davis, showed that Carotenoid Complex protected LDL (so-called “bad” cholesterol) from oxidation. In fact, the concentration of beta-carotene, a compound that indicates absorption of carotenoids, increased five-fold in the LDL of people who supplemented with three capsules of Carotenoid Complex daily for 20 days. This finding is significant because LDL oxidation is believed to be a major initiator of atherosclerosis and heart disease.(3)
In the study, healthy women were fed a low-carotenoid diet for 100 days. Then, for the remaining 20 days of the study, this diet was supplemented daily with three capsules of Carotenoid Complex. The carotenoid content of the LDL rose dramatically. “The results indicate that increased carotene consumption may have a protective effect against oxidative stress in vivo, suggesting that a low carotene intake may increase the oxidative susceptibility of body lipids,” the researchers concluded.
Scientists have learned through decades of research that free radicals are a major threat to the health of your cells. Free radicals constantly attack and damage cells. Your body’s best line of defense against free radical damage is powerful antioxidants, such as Carotenoid Complex. Two independent published studies conducted by researchers at the United States Department of Agriculture (USDA), in affiliation with three universities, demonstrated that GNLD International’s Carotenoid Complex, a whole-food dietary supplement made from fruits and vegetables, protected cells from oxidation.(4,5)
Another study, conducted by researchers at Florida International University (Miami), the University of Washington (Seattle), and the USDA’s Western Human Nutrition Research Center (San Francisco), showed that three capsules of Carotenoid Complex per day prevented the oxidation of cellular lipids. Beta-carotene alone (0.5 mg) did not cause a significant decrease in oxidation. In contrast, Carotenoid Complex, a broad-spectrum supplement including alpha-, beta-, gamma-, and zeta-carotene, lycopene, lutein, cryptoxanthin, and other naturally occurring fruit and vegetable carotenoids, caused a 44% decrease in oxidation. The finding is important because oxidation contributes to the decline of the body’s defence and many aggressive threats to the body’s overall well being.
The study also demonstrated that carotenoids are necessary even when people consume diets plentiful in other antioxidants, including preformed vitamins A, E, and C. The study ran for 120 days, during which time nine healthy young women lived in the metabolic research unit of the USDA’s Western Human Nutrition Research Center, where diet, exercise, and other activities were controlled. The researchers concluded that the findings provide evidence to support the beneficial effects of carotenoids in preventing lipid peroxidation in cells.(4,5)
(1) Carughi, A & Hooper, FG. Plasma carotenoid concentrations before and after supplementation with a carotenoid mixture. Annuls of the New York Academy of Sciences, Vol. 691: 244-245, 1993.
(2) Carughi, A & Hooper, FG. Plasma carotenoid concentrations before and after supplementation with a carotenoid mixture. American Journal of Clinical Nutrition, Vol. 59 (4): 896-899, 1994.
(3) Dixon, ZR, Burri, BJ, Clifford, A, Frankel, EN, Schneeman, BO, Parks, E, Keim, NL, Barbieri, T, Wu, M, Fong, AKH, Kretsch, MJ, Sowell, AL, Erdman, JW. Effects of a carotene-deficient diet on measures of oxidative susceptibility and superoxide dismutase activity in adult women. Free Radical Biology and Medicine. Vol. 17 (6): 537-544, 1994.
(4) Dixon, ZR, Shie, FS, Warden, BA and Burri, BJ. Effect of Low Carotene Diet on Malondialdehyde (MDA) Concentration. FASEB J. 10:A240, 1996.
(5) Dixon ZR; Shie FS; Warden BA; Burri BJ; Neidlinger TR. The effect of a low carotenoid diet on malondialdehyde-thiobarbituric acid (MDA-TBA) concentrations in women: a placebo-controlled double-blind study. Journal of the American College of Nutrition, Feb 1998, Volume 17(1):54-8.
(6) Kramer, TR, Burri, BJ, and Neidlinger, TR. Carotenoid/Flavonoid Modulated Immune Response in Women, USDA Beltsville, Human Nutrition Research Center, San Francisco, California. Proceedings of the annual meeting of Professional Research Scientists Federation of American Societies of Experimental Biology. 9-13 April 1995.
(7) Kramer TR; Burri BJ. Modulated mitogenic proliferative responsiveness of lymphocytes in whole-blood cultures after a low-carotene diet and mixed-carotenoid supplementation in women. American Journal of Clinical Nutrition. Vol. 65(3): 871-875, Mar. 1997.